University of Sheffield – The Bateson Centre Small Molecule Screening Unit

The Bateson Centre Small Molecule Screening Unit (BSMSU) is a multiuser, cross-disciplinary facility that specialises in drug discovery using a wide range of assays. Predominantly it provides a platform for whole-organism (zebrafish) in vivo screens for researchers that are studying a range of developmental and disease mechanisms.  The facility may also be used to identify new potential therapeutic small molecules or test drug toxicities. It supports innovative collaborations with both academic and industrial partners. The Bateson Centre is hosted within the Department of Biomedical Science and benefits from close ties with the Centre for Stem Cell Biology (CSCB) and the Centre for Membrane Interactions and Dynamics (CMIAD).


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Principal Disease Indication(s)

Zebrafish models of disease, including epilepsy, inflammation, infection, hypoxia, ototoxicity


Platform(s)

Small molecules


Technology(ies):

HCI, MPA, HTS plate reader, microscopy


Funding sources:

MRC, BBSRC, charities, industry


Personnel:

2


Number of Screens / year (any size):

5-10


Medicinal Chemistry Follow-up:

No


Contact Details

Dr Sarah Baxendale

Phone: +44 (0)114 222 2377
www.bateson.group.shef.ac.uk

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Getting there

Address: 309 Western Bank, Sheffield, South Yorkshire S10 2TJ, UK
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